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Smallpox breaks out in rome, killing 5,000,000 in 15 years.
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Mesopotamia falls to the Persians, further spreading mesopotamian agriculture and culture into the middle east and some parts of Europe
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Germanic migration from Rome outwards due to small tribe rebellion begins.
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The Bubonic Plague kills 25,000,000 people in the Byzantine empire, severely hurting Romes population, agriculture, and status among countries.
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The black death kills 100,000,000 in Europe and Asia combined.
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Population growth starts to even back out after the black death
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Europeans brought numerous diseases that natives bodies weren't accustomed to, resulting in 90 to 95% of the native population dying of disease.
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With the arrival of Europeans to the Amazon, the rainforest started to be burned and cut down to be used as farmland and land for cattle.
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The trans-atlantic slave trade started the largest movement of people ever recorded and consisted of West Africans being forced to move to the Americas for labor.
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The great potato famine started some of the most prominent migrations which consisted of hundreds of thousands of Irish moving to the Americas in order to aqquire food since there was a lack of food in Ireland.
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European nations colonize Africa to use the environment for resources and other things they were running out of.
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The population of Africa, Asia, and Europe dropped, while the population in North America rose.
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Aerosol spray can was invented in 1926 by an inventor Eric Rotheim, which started the depletion of the ozone layer and changed the way humans interacted with their environment.
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Population begins to even back out after the great famine killed around half of Irelands population.
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The plague of Emmaus which was actually the Bubonic plague occured in Pakestan, killing 25,000
