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When Columbus and his men landed in America he brought many diseases such as small pox, measles, flu, whooping cough, typhus, chlorea, scarlet fever. These diseases killed many of the Native Americans.
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Mass-execution before the arrival of Columbus, the land numbered in 12 million. Four centuries later, it had been reduced by 95%.
When Columbus returned in 1493 he brought an army of 17 ships. Slavery and mass-extermination was big of the Taino population of the Caribbean. Within three years five million were dead. -
The United States adopted a policy toward American Indians known as the "conquest" theory. The Iroquois had to ceced lands in western New York and Pennsylvania.
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By the 1820’s the Cherokees, who had established a written constitution, a newspaper, schools, and industries in their settlements, resisted removal.
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The “Indian Removal” policy was put into action to “clear" land for white settlers. Forced marches at bayonet-point to relocation settlements resulted in high death rates. The removal of the Five Civilized Tribes — the Choctaws, Creeks, Chickasaws, Cherokees, and Seminoles — is an important event in United States history.
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Pequot Indians were exterminated by the colonist when they burned their villages in Mystic, Conneticut, and then shot all the other people, including women and children, who tried to escape.
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In 1938 the federal troops evicted the Cherokees. About 4,000 died and was later known as the Trail of Tears. More than one hundred thousand American Indians eventually crossed the Mississippi River under the authority of the Indian Removal Act.