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The missouri Compromise of 1820 drew the line across the Louisiana Territory that separate free and slave territories.
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A slave name Nat turner invited an uprising that spread through several plantations in Southern Virginia.
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The Compromise of 1850 allowed California to enter as a free state, while other new territories decided the issue fo slavery through popular sovereignty.
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In Kansas-Nebraska Act allowed popular sovereignty in Kansas and Nebraska causing proslavery and antislavery settlers to flock to Kansas.
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Lincoln's reputation for integrity gained him the Republican nomination for President. The republicans anti slavery outlook was a big factor towards the cival war
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After the Union commander refused to give up the fort, Confederate troops fired on it until the federal troops surrendered. The fall of fort sumter marked the start of the Civil War.