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Frederick Griffith
Conducted experiment with bacterium and mice which was the first to reveal the “transforming principle,” which led to the discovery that DNA acts as the carrier of genetic information. -
Frederick Griffith Exepriment
Griffith concluded that the R-strain bacteria must have taken up what he called a "transforming principle" from the heat-killed S bacteria, which allowed them to "transform" into smooth-coated bacteria and become virulent. -
Oswald Avery
He further explored Frederick Griffith showed that DNA was the "transforming principle." Saying that it played an important role in traits and carrying information not the proteins. -
Oswald Avery Experiment
In a very simple experiment, Oswald Avery's group showed that DNA was the "transforming principle." When isolated from one strain of bacteria, DNA was able to transform another strain and confer characteristics onto that second strain. DNA was carrying hereditary information. -
Erwin Chargaff
Studied DNA itself in terms of structure. Erwin Chargaff found that in DNA, the ratios of adenine (A) to thymine (T) and guanine (G) to cytosine (C) are equal. and that bases paired with each other. -
Erwin Chargaff Disocvery
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Rosalind Franklin
Rosalind Franklin discovered the density of DNA and, more importantly, established that the molecule existed in a helical conformation. Her work to make clearer X-ray patterns of DNA molecules laid the foundation for James Watson and Francis Crick's suggestion that DNA is a double-helix polymer in 1953. -
Rosalind Franklin Experiment
By improving her methods of collecting DNA X-ray diffraction images, Franklin obtained Photo 51 from an X-ray crystallography experiment she conducted on 6 May 1952. First, she minimized how much the X-rays scattered off the air surrounding the crystal by pumping hydrogen gas around the crystal. -
Hershey and Chase
Hershey is most noted for the so-called blender experiment that he performed with Martha Chase in 1952. By showing that phage DNA is the principal component entering the host cell during infection, Hershey proved that DNA, rather than protein, is the genetic material of the phage. -
Hershey and Chase Experiment
The Hershey-Chase experiments settled the long-standing debate about the composition of genes, thereby allowing scientists to investigate the molecular mechanisms by which genes function in organisms. In the early twentieth century, scientists debated whether genes were made of DNA or protein. -
Watson and Crick
Watson and Crick worked together on studying the structure of DNA (deoxyribonucleic acid), the molecule that contains the hereditary information for cells. Created by Rosalind Franklin using a technique called X-ray crystallography, it revealed the helical shape of the DNA molecule. Watson and Crick realized that DNA was made up of two chains of nucleotide pairs that encode the genetic information for all living things. -
Watson and Crick experiment
Watson and Crick showed that each strand of the DNA molecule was a template for the other. During cell division the two strands separate and on each strand a new "other half" is built, just like the one before.