Causes of the Civil War By facebooker_1775648055988456 Jan 1, 1820 Missouri Compromise Period: Apr 25, 1846 to Feb 2, 1848 Mexican War Aug 8, 1846 Wilmot Proviso Jan 1, 1850 Compromise of 1850 Mar 20, 1854 Republican Party Formed Mar 20, 1854 Uncle Tom's Cabin May 30, 1854 Kansas-Nebraska Act Period: Jan 1, 1855 to Jan 1, 1861 Bleeding Kansas Jan 1, 1857 Dred Scott v. Sandford Jan 1, 1858 Lincoln-Dpuglas Debates Oct 17, 1859 Harper's Ferry Jan 1, 1860 Election of 1860 Dec 20, 1860 South Carolina Secedes Period: Apr 12, 1861 to Apr 14, 1861 Fort Sumter