1845 to 1860 By Crater200 Period: Jan 1, 1845 to Dec 25, 1860 Events from 1845-1860 Apr 25, 1846 The start of the Mexican War Aug 8, 1846 Wilmot Proviso Feb 2, 1848 The end of the Mexican War Sep 1, 1850 The Compromise of 1850 Mar 20, 1852 Uncle Tom's Cabin comes out as a book. Jan 1, 1854 Congress passes the Kansas-Nebraska Act Jul 6, 1854 Republican Party officially organizes. May 21, 1856 Proslavery attack on Lawrence Kansas. May 22, 1856 The caning of Charles Sumner May 24, 1856 Pottawatomie Creek Massacres Oct 16, 1856 John Brown's raid on Harper's Ferry Mar 6, 1857 Dred Scott decision Aug 21, 1858 Lincoln-Douglas Debates Nov 6, 1860 The Election of 1860-Lincoln wins! Dec 20, 1860 South Carolina secedes