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1616, 1633, 1713, 1721, 1732, 1747, 1788, thousands of deaths in Boston, spreading in crowded cities, and decimating native Indian populations, symptoms indicate possibly yellow fever, bubonic plague, influenza, smallpox, measles, chickenpox, typhus.
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5,000 deaths in Philadelphia, followed by 25 different outbreaks across the country over the next century, possibly brought by slaves or merchants from Africa or Caribbean and spread by mosquitos;
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Affected millions worldwide 1832, 1848, 1866. By the early 1800's, the British Empire had grown to be the largest empire in world history, controlling over 13 million square miles and ruling over a half billion people.
It was the first truly global disease, killing tens of millions in crowded cities in:
England, Ireland, Belgium, Netherlands, France, Spain, Italy, Germany, Hungary, China, Japan, Java, Korea, the Philippines, India, Bengal, Iran, Iraq, Algeria, Tunisia, Egypt, Arabia, and Africa. -
Affected over 20,000, mostly children.
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Affected over 100,000 during Civil War and Spanish America War
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Caused 100,000 deaths per year.
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Eventually peaking with 60,000 children infected in 1952, hundreds of thousands of paralytic cases worldwide.
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75 million worldwide
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200,000 cases a year through the 1920s;
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2 million deaths worldwide.
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1 million deaths worldwide.