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The first outbreak of the Black Plauge in Asia due to trade routes to Silk Road (from Asia, Eurasia and Europe). -
During the Black Death in the 14th century, Lake Issyk Kul in Central Asia was unaffected due to its isolation, preserving the region's inhabitants from the devastating plague. -
During the Black Death, the Lower Volga River region in Russia experienced significant population decline due to the pandemic, with devastating consequences for local communities and trade. -
In the Black Death era, Crimea and the Caucasus were affected by the pandemic. These regions experienced death tolls and socioeconomic disruptions due to the plague's impact on trade and population. -
Messina, Sicily, in the Black Death era saw a catastrophic outbreak, with high mortality. The plague's arrival via trade routes caused widespread death, chaos, and societal upheaval. -
Egypt, a major trade and transport hub in the Black Death era, experienced a severe pandemic. The plague's arrival led to significant death tolls and socioeconomic disruptions in the region. -
During the Black Death, Italy and Greece endured devastating outbreaks, leading to significant population decline and social upheaval. Trade routes contributed to the spread of the pandemic in these regions. -
Britain and Ireland witnessed the Black Death's grim impact in the 14th century. The plague, likely brought by ships, led to substantial death and significant societal consequences. -
In the Black Death era, Alexandria, Egypt, suffered a devastating outbreak. The plague's arrival via trade routes and dense urban populations led to widespread death and societal disruption. -
During the Black Death, Genoa and Venice, as major Mediterranean ports, faced severe outbreaks. The plague disrupted trade and caused substantial loss of life in these maritime cities. -
Constantinople, the Byzantine capital, suffered a grim fate during the Black Death. The pandemic decimated the city's population and contributed to the weakening of the Byzantine Empire. -
In Northern Europe, the Black Death's relentless spread in the 14th century caused widespread mortality, altering the region's social and economic dynamics while reshaping its demographic landscape. -
Mecca, the holiest city in Islam, faced the ravages of the Black Death during the 14th century, leading to a significant loss of life and religious disruptions. -
Yemen, a critical trade hub, was not spared from the Black Death. The pandemic brought death and economic turmoil to the region, disrupting commerce and society in the 14th century. -
In the 14th century, Moscow endured the Black Death, which caused significant loss of life and social upheaval, contributing to the city's historical experience during this pandemic.