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In1492, Christopher Columbus of Span sails to the Americas in search of wealth and glory.
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This was the first ever Spanish colony, existing on the coast of central America.
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Smallpox arrives on the island of Hispaniola. A century later, only about 5 percent of the island's population remained.
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In 1532, spaniard Fransisco Piazarro and 600 of his men arrived in the New World to encounter the Inca, soon wiping out this American Empire as a whole.
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The Spanish opened mines to send 30,000 tons of silver to Spain per year. Local slaves were used to cheaply produce lots of profit.
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The brother Shawnee prophets share their visions toward Indian unity.
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A half-century war between the Indians and Mexicans