Anne Catherine Hoof Green takes over her late husband's printing and newspaper business, becoming the first American woman to run a print shop. The following year she is named the official printer for the colony of Maryland.
The first public high school for girls opens in Worcester, Massachusetts.
Antoinette Blackwell becomes the first American woman to be ordained a minister in a recognized denomination (Congregational).
Lucy Hobbs becomes the first woman to graduate from dental school, the Ohio College of Dental Surgery.
In Wyoming, for the first time in U.S. history, women are allowed to serve on a grand jury.
Susanna Medora Salter becomes the first woman elected mayor of an American town, in Argonia, Kansas.
Mary Kies becomes the first woman to receive a patent,
Alice Guy Blaché, the first American woman film director,
March 12, the first Girl Scouts troop in America is founded in Savannah, Georgia, by Juliette Gordon Low.
Mary Davenport-Engberg is the first woman to conduct a symphony orchestra, in Bellingham, Washington.
Maxine Dunlap becomes first American woman to earn a glider pilot license.
Hattie Caraway of Arkansas becomes the first woman elected to the U.S. Senate
The Women's Auxiliary Army Corps (WAAC) is established in the United States.
Edith Houghton becomes the first woman hired as a first major-league baseball scout
Oveta Culp Hobby becomes the first woman to serve as Secretary of Health, Education, and Welfare
Jerrie Cobb is the first woman in the U.S. to undergo astronaut testing.
The Equal Pay Act makes it illegal for companies to pay different rates to women and men who do the same work.
Diane Crump becomes the first female jockey to ride in the Kentucky Derby.