DNA: The Genetic Material Timeline

  • P.A. Levene- Nucleotides

    P.A. Levene- Nucleotides
    P.A. Levene discovered the basic structure of nucleotides that make up DNA. He discovered that the nucleotides are the subunits of nucleic acids and consist of five-carbon sugar, a phosphate group, and a nitrogenous base.
  • Period: to

    DNA Timeline

    This is a timeline of important people that were involved with DNA.
  • Fredrick Griffith

    Fredrick Griffith
    Fredrick Griffith conducted the first experiment that led to the discovery of DNA as the genetic material. He studied two strains of the bacteria Streptococcus pneumoniae. He discovered that one strain could be transformed into the other form. His experiment set the stage for the search to identify the transforming substance.
  • Oswald Avery

    Oswald Avery
    Oswald Avery, and his collegues, identified the molecule that transformed the R strain of bacteria into the S strain. Oswald Avery then conducted an experiment, but it was not really accepted by the scientific community. But, he did narrow the choices down to either that DNA or proteins were the cause of the transformation
  • Erwin Chargaff

    Erwin Chargaff
    Erwin Chargaff analyzed the amount of adenine, guanine, thymine, and cytosine in the DNA of various species. He found that the amount of guanine nearly equals the amount of cytosine, and the amount of adenine nearly equals the amount of thymine within a species. Chargaff's Rule was created.
  • Rosalind Franklin- X-Ray Diffraction

    Rosalind Franklin- X-Ray Diffraction
    Rosalind Franklin joined the staff at King's College. When she was there, she took the now famous Photo 51 and collected important data eventually used by Watson and Crick. Photo 51 showed that DNA was double helix, formed by two nucleotides twisted together. She discovered the specific structure, which was that DNA was a double helix, by using X-Ray Diffraction.
  • Maurice Wilkins

    Maurice Wilkins
    Maurice Wilkins was working at King's College in England, with a technique called X-Ray Diffraction, it involved aiming X-Rays at DNA molecules. Wilkins worked with Franklin and showed her the X-Ray Diffraction.
  • Hershey and Chase

    Hershey and Chase
    Alfred Hershey and Martha Chase published results of experiments that provided definate evidence that DNA is the transforming factor of Oswald Avery's work. The experiments conducted involved bacteriophage. Two components made it clear that DNA was the transforming factor, first, the bacteriophage being used was made of protein and DNA, and second, viruses can't replicate themselves. They then used Radioactive Labeling and the traced the DNA.
  • James Watson- DNA Structure

    James Watson- DNA Structure
    James Waton and Francis Crick were working at a University in England when they then saw Franklin's X-Ray Diffraction pictures. Using Chargaff's and Franklin's data, they measure the width of the helix and the spacing of the bases. Then, together, they built a model of the double helix. There were three important features about the molecule.
  • Francis Crick- DNA Structure

    Francis Crick- DNA Structure
    James Waton and Francis Crick were working at a University in England when they then saw Franklin's X-Ray Diffraction pictures. Using Chargaff's and Franklin's data, they measure the width of the helix and the spacing of the bases. Then, together, they built a model of the double helix. There were three important features about the molecule.
  • Linus Pauling

    Linus Pauling
    Linus Pauling demonstrated the first attempt to the structur of triple helix DNA. Although it was incorrect, it was a huge step and gave background information as well as a base to start at.
  • Sites used

    The only two sites I used were the Biology online textbook and google [Google Images](http://images.google.com/)<ahref='http://moodle.berea.k12.oh.us/mod/resource/view.php?inpopup=true&id=47397' >Online Biology Textbook</a>