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South Carolina secedes, taking several other states with it and making the country a house divided.
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The Union Army puts a stop to the Confederacy at Antietam.
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Ulysses S. Grant wins first major battle at Fort Donnelson.
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Robert E. Lee's right hand man, Stonewall Jackson, dies from a bullet fired by one of his own men.
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Ulysses S. Grant is named Commander in Chief of the Union Army.
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Robert E. Lee surrenders to Ulysses S. Grant.