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Christopher Columbus signs contract with Spain to find Indies.
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Christopher Columbus returns to Spain from Palos.
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The Treaty of Tordesillas signed by Spain and Portugal, for partitioning the World.
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The first African slaves arrived in North America.
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Fourth and final voyage of Christopher Columbus leaves from Cadiz, Spain, with four ships.
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Christopher Columbus dies in Valladolid, Spain.
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Hernan Cortes sets sail from cuba with 16 horses and a few hundred men.
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Ferdinand Magellan sails around the world.
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He takes 570 men on an expedition to present day Tampa.
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Hernando de Soto dies in Desha County, Arizona from a bad fever.
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French defeated Spanish at Ceresole Battle
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Hernando Cortes dies in Castilleja de la Cuesta, Spain from pleurisy.
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Elizabeth I becomes Queen of England.
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Galileo Galilei was born.
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The Spanish Armada got defeated by the English.
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Traversed the bare Sonora Desert from Mexico into the Rio Grande Valley.
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The population of American colonists reaches 475,000.
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Slavery was abolished in Russia
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50 African American slaves are hung in Charleston South Carolina.
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Cotton Mills were first opened in England.
