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English settlement by the London company
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Smallpox pandemic kills 90% of the Native American population
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Defenestration of Prague begins the most devastating war in European history
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The first slaves arrive in the New World, Jamestown
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The House of Burgesses meet in Virginia for the first time
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The earliest human-powered submarine was invented
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The Pilgrims arrived in the New World and founded Plymouth
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The first college in North America, Harvard College is founded in Cambridge, Massachusetts
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Massachusetts becomes first state to legalize slavery
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James Gregory invents the first reflecting telescope
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Uprising of the Natives against the inhabitants of New England
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