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In 1492, Christopher Columbus sailed the ocean in search of a trade route to India.
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In 1511, the first Africans arrived in America. Part of the Columbian Exchange, Africans would be taken by the thousands to America.
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Cortés conquers Aztec Empire in 1521.
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Pizarro conquers the Incan Empire in 1533.
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In 1607, the English founded Jamestown.
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In 1620, the English founded Plymouth.
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In 1763, the French and Indian War ended.