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At age 14, Knight begins attending MIT, taking courses in computer programming and organic chemistry.
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Develops the original kernel for the Incompatible Timesharing System (ITS) at MIT.
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Designs and supervises the construction of the first PDP-10 ARPANET interfaces with Bob Metcalfe
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Creates one of the first semiconductor memory-based bitmap displays, influencing modern graphical interfaces.
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Designs and implements the prototype version of the MIT Lisp Machine processor
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Collaborates with Jack Holloway to design and implement Chaosnet, MIT's first local area network
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Participates in developing the Connection Machine architecture, advancing parallel processing.
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Shifts focus to biology, establishing a molecular biology lab within MIT's Computer Science department
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Leads a DARPA-funded study on cellular computing, merging computational and biological sciences.
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Introduces BioBricks, standardized DNA sequences facilitating genetic engineering.
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Co-founds the International Genetically Engineered Machine (iGEM) competition, promoting synthetic biology education.
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Co-founds Ginkgo Bioworks, focusing on designing custom organisms for various applications.
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Ginkgo Bioworks secures significant funding to expand its organism design platform.
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Ginkgo Bioworks goes public, trading under the ticker symbol "DNA."
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Knight continues to influence synthetic biology through his work at Ginkgo Bioworks and contributions to iGEM.