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Spain was not united for a while but they became united as a plan to strengthen spain even further.
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This marks a beginning of interest in expansion and exploration in Columbus.
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This starts to further the explorers ideas on where they could go to get the most land and power.
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First successful colony, in Virginia, settled in 1607 that helped to start out the Americas
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the end of the first major conflict between the europeans and the natives in America.
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This marked the beginning of the idea that conflict with the natives would be a constant issue.