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1492
first voyage by Columbus to the western hemisphere
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1494
Treaty of Tordesillas
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1498
founding of Santo Domingo
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1500
Brazil claimed for Portugal by Pedro Alvarez de Cabral
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1515
social disruption and physical abuse brought decline to Taíno populations on the large Carribbean islands
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1518
smallpox epidemic in the Caribbean
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Period: 1519 to 1521
Spanish conquest of Mexico
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1520
smallpox spread to Peru
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1525
execution of Cuauhtémoc
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Period: 1532 to 1540
Spanish conquest of Peru
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Period: 1532 to 1533
Francisco Pizarro and his followers toppled the Inca empire in Peru
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1535
Spanish founded Lima
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1545
Spanish discovery of silver near Potosí
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1560
smallpox and measles ravage the whole Brazilian coast
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1560
Jean Nicot introduces tobacco use to Paris
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1565
Spanish mariners inaugurate the Manila galleon trade between Manila and Acapulco
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foundation of Port Royal (Nova Scotia)
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foundation of Jamestown
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foundation of Quebec
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foundation of New Amsterdam
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foundation of the Massachusetts Bay Colony
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Virginia law recognized all blacks as slaves
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native groups in northern Mexico mount the Pueblo revolt
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smallpox epidemic on Guam
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Period: to
French and Indian war in North America
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transfer of French Canadian possessions to British rule
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Period: to
Captain James Cook's exploration of the Pacific Ocean
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Captain James Cook crossed the Hawaiian islands
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native peoples revolt in the name of Túpac Amaru
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establishment of the first European colony in Australia