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The first time we knew something bout a pandemic: Sonia Pestis killed a lot of people on the Bizantine Empire
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Probably the only pandmic the people know about, the bubonic pest killed 200000 million persons or so in all the world.
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The europeans wanted the American Lands so they spread virus to people that thought they were gods and killed 20 million persons or so
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If you thought the First WW was bad, there was a virus that is called Spanish Flu only for not desmotivate the soldiers and it killed 50millions of innocent people.
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Also known as the new Black Death, this virus is killing people right now but people things that is just a govverment´s idea.