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The plague was carried by fleas on sailing vessels returning from the ports of Asia, spreading quickly due to lack of proper sanitation: the population of England, www.themiddleages.net/plague.html
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plague which was ravaging Florence in 1348.www.themiddleages.net/plague.html
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It began in Northern Italy about 1350 right after the Black Death had ravaged the country
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from 1350 to 1550, new techniques evolved in the fields of painting, sculpture, and architecture.
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The Avignon Papacy was followed by the Great Schism, when two or sometimes three popes denounced each other, until 1417
https://en.wikipedia.org/wiki/Renaissance_Papac -
The term first appears in Latin in 1469 as media tempestas
https://en.wikipedia.org/wiki/The_Tempest_(Giorgione) -
One memorable humanist historian and forerunner of modern political thought was NICCOLO MACHIAVELLI (1469-1527).
https://en.wikipedia.org/wiki -
the discovery of the New World by Christopher Columbus challenged the classical world-view, as the works of Ptolemy (geography) and Galen (medicine) were found not always to match everyday observations:
https://en.wikipedia.org/wiki/ -
In an era following the sack of Rome in 1527 and prevalent with uncertainties in the Catholic Church following the Protestant Reformation, Pope Paul III came to the papal throne
https://en.wikipedia.org/wiki/Pope_Paul_II -
Henry in 1535 after his former Lord Chancellor, a loyal Catholic, had refused to recognize the king as the supreme head of the Church of England.
www.britroyals.com/kings.asp?id=henry8