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This timeline illustrates the struggle between the North and the South over the slavery issue. Time and time again they reached compromises only to have them fall apart.
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The Missouri Compromise was an agreement between the North and the South that allowed for Missouri to come in as a slave state and Maine would become a free state. Also a line was drawn above which slavery would not be permitted. This was the start of many compromises that tried to solve the slavery question without war.
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descriptions here