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Anna or Brittany announces that all those who would ally with the king of France would be considered gullty of the crime of lese-mejesty
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Christopher Columbus started to sale the ocean
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Christopher Columbus left Spain on his fourth voyage to the New World, landing back on the islands of Martinique and Jamaica in June. This voyage would take him to Central America, but not to North America.
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Marriage between Emperor Charles V of Spain and ruler of the Holy Roman Empire and Isabella of Portugal, the sister to King John III, defuses disagreement over Treaty of Tordesillas and partitioning of New World territory between Spain and Portugal.
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The first war between native Americans and Europeans in the southwest occurs between troops of Coronado and the Tiwa Indians. The Tiguex war was waged near Bernalillo, New Mexico against the dozen pueblos of the tribe on the American and Mexican sides of the Rio Grande River.
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Battle of Ivry: French King Henry IV beats Catholic League during French Wars of Religion
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Dutch and English army led by Maurice of Nassau captures heavily protected city of Breda using a small assault force hidden in a peat barge
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Immigration started