History ADN

  • Discovery of nucleic acids

    Discovery of nucleic acids

    Isolated the genetic material from white blood cell nuclei. He noted it had an acidic nature and called it nuclein.
  • Discovery of DNA components, Phoebus Levene, (1869-1940)

    Discovery of DNA components, Phoebus Levene, (1869-1940)

    ·Determined the components of DNA:
    ·adenine, guanine, thymine, cytosine, deoxyribose, posphate
    ·Defined phosphate-sugar-base units called (nucleotides).
  • Frederick Griffith, Britsh bacterologist, (1879-1941)

    Frederick Griffith, Britsh bacterologist, (1879-1941)

    ·Studied the epidemiology and pathology of 2 strains of Streptococcus pneumoniae.
    In January 1928 reported the first widely accepted demonstration of bacterial transformation.
  • Maurice Wilkins, New zeland Physicist, (1916-2004)

    Maurice Wilkins, New zeland Physicist, (1916-2004)

    Around 1951-1952, he was studying DNA fibers with X-ray diffraction and shared some results (without Franklin's knowledge) that later helped Watson and Crick.
  • Rosalind Franklin, British Biophysicist, (1920-1958)

    Rosalind Franklin, British Biophysicist, (1920-1958)

    Between 1951 and 1953, she produced very clear X-ray diffraction images of DNA, including the famous Photo 51, which was crucial for confirming the double helix structure.
  • Counting Nucleobases, Erwin Chargaff, Austrian biochemist, (1952-2002).

    Counting Nucleobases, Erwin Chargaff, Austrian biochemist, (1952-2002).

    Used paper chromatography and UV spectroscopy to examine the abundance of the nucleobases and he to notice, and he started to notice something VERY odd…
  • Hershey-Chase Experiment, Martha Chase, American geneticist, (1952)

    Hershey-Chase Experiment, Martha Chase, American geneticist, (1952)

    She was his research assistant who carried out of the experiment, using radioactive labeling to show that DNA, not proteins, carry genetic material.
  • Hershey-chase Experiment, Alfred Hershey

    Hershey-chase Experiment, Alfred Hershey

    He was a scientist who worked with bacteriophages and helped design the famous experiment that tested whether DNA or proteins carry genetic information
  • Triple Helix? Linus pauling, Americant biochemist,

    Triple Helix? Linus pauling, Americant biochemist,

    Linus Pauling and Robert Corey proposed a triple helix structure for DNA. Just before Watson and Crick published their double helix model.