Christopher Columbus By April_Marie Oct 31, 1451 Happy Birthday Christopher! Period: Oct 31, 1451 to May 20, 1506 Christopher Columbus Apr 10, 1473 Columbus began his apprenticeship as business agent May 16, 1478 In May 1476, he took part in an armed convoy sent by Genoa to carry a valuable cargo to northern Europe. Jul 12, 1479 Christopher Columbus married a noblewoman called Felipa Perestrello Moniz. Sep 6, 1479 Columbus reached his brother Bartolomeo in Lisbon, while continuing trading for the Centurione family Feb 17, 1480 his son Diego Columbus was born Aug 3, 1492 Columbus set sail Nov 21, 1492 the Pinta and its crew left to explore on its own. Mar 5, 1493 Christopher Columbus arrives at Palos in Spain bringing his news of the New World Nov 7, 1504 Christopher Columbus returns to Spain May 20, 1506 Christopher Colmbus died.