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The first permanent settlement in America, Jamestown, is established by the London Company. It was established in Southeast Virginia.
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Smallpox killed nearly 90% of the Massachusetts Bay Native Americans.
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The first African slaves were brought to America near Jamestown.
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The first representative assembly, The House of Burgesses, meets for the first time.
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In Massachusetts, the Plymouth Colony is established by Pilgrims from England.
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The Mayflower Compact was signed by 41 men to agree on the basics of their colonies government.
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The Province of Maryland is founded.
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the Crown, or King of England, formally accepted and recognized the Virginia Assembly.
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The English seize New Amsterdam from the Dutch, and rename it New York.
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Charles Town was founded in the Province of Carolina.