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Jamestown, the first permanent English settlement in America.
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Smallpox epidemic wipes out 90% of the Native Americans in the Massachusetts Bay area.
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The House of Burgesses, the first representative assembly in America, meets for the first time
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The Plymouth Colony in Massachusetts is established. The Mayflower Compact is signed.
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The first Thanksgiving celebration is held.
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October 28, 1636 - Harvard College is founded in Cambridge, Massachusetts.
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Colonial population is estimated at 50,400.
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English seize New Amsterdam from the Dutch and rename it New York.