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March 4, 1861, seven cotton states declared their secession and joined together to form the Confederate States of America.
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Hostilities began on April 12, 1861, when Confederate forces attacked a U.S. military installation at Fort Sumter in South Carolina. Lincoln responded by calling for a volunteer army from each state to recapture federal property, which led to declarations of secession by four more slave states.
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In September 1862, the confederate campaign in Maryland ended in defeat at the Battle of Antietam, which dissuaded the British from intervening.Days after that battle, Lincoln issued the Emancipation Proclamation, which made ending slavery a war goal
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In 1863, confederate general Robert E. Lee's northward advance ended in defeat at the Battle of Gettysburg. To the west, the Union gained control of the Mississippi River after the Battle of Shiloh and Siege of Vicksburg, thereby splitting the Confederacy in two and destroying much of their western army.
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Due to his western successes, Ulysses S. Grant was given command of the eastern army in 1864, and organized the armies of William Tecumseh Sherman, Philip Sheridan and others to attack the Confederacy from all directions, maximizing the North's advantage in manpower. Grant restructured the union army, and put other generals in command of divisions of the army that were to support his push into Virginia
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When the Confederate attempt to defend Petersburg failed, the Confederate army retreated but was pursued and defeated, which resulted in Lee's surrender to Grant at Appomattox Court House on April 9, 1865