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The Black Plauge killed about 1.5 million people from the total 4 million in Europe in that time. Since there was no medical knowledge about the disease, there was no way of stopping it from spreading and killing.
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The age of the Renaissance was a cultural movement that spanned the period roughly from the 14th to the 17th century, beginning in Italy in the Late Middle Ages and later spreading to the rest of Europe. Also included a huge artistic movement.
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The Siege of Orléans (1428–1429) marked a turning point in the Hundred Years' War between France and England. This was Joan of Arc's first major[5] military victory and the first major French success to follow the crushing defeat at Agincourt in 1415.
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Spanish Inquisition Begins
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Cosimo died on August first, 1464 he was the first of the Medici political dynasty, de facto rulers of Florence during much of the Italian Renaissance; also known as "Cosimo 'the Elder'" and "Cosimo Pater Patriae" (Latin: 'father of the nation'). After his death the Signoria awarded him the title Pater Patriae, "Father of his Country"