Renaissance timeline, N.W. , per 3 By Nicholas.W Period: 1347 to 1353 Black death the bubonic plague killed thousands of people. Period: 1400 to 1495 early ren there was new discovery's in science. Period: 1495 to 1527 high ren Leonardo da Vinci created the last supper. Period: 1527 to 1610 late ren the development of humanism grew rapidly.