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Giotto completes the Scrovegni Chapel in Padua
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Dante writes Divine Comedy
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Bubonic Plague
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Early Renaissance
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Architect Brunelleschi designs the dome for the Florence Cathedral
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Joan of Arc and the Siege of Orleans
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The Medici family becomes the head of the city-state of Florence.
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The Ottoman Empire captures the city of Constantinople, signaling an end to the Byzantine Empire.
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Johannes Gutenberg invents the printing press.
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