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The bacterium responsible has been identified as your Sania pestis commonly known as bubonic plague a pathogen carried by rats and transfered to humans through fleas. 25 to 50 million people had died.
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Ships returned to the shores of Sicily filled with sailors stricken by a mysterious illness that formed dark sweelings or buboes and the armpits and groin this symptom led to the nickname Black Death. The Venetians banned sailors from entering their cities for 40 days. While these quarantine efforts did help to deter the outbreak in the end the Black Death took up to 200 million live across Eurasia.
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Perhaps we are still feeling the aftereffect of the horrendous Spanish Flu to this day the most recent mass pandemic struck in 1918 an infected 500 million worldwide unlike most diseases. Spanish Flu impacted young adults the hardest half of those that died were between the ages of 20 and 40 and 99% were under the age of 65. By the end of 1920 Spanish Flu claimed the lives of 50 to 100 million
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The COVID-19 pandemic is a pandemic derived from the coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus (severe acute respiratory syndrome coronavirus type 2). It was first identified in December 2019 in the city of Wuhan, capital of Hubei province, in the People's Republic of China. Recognized as a pandemic by the World Health Organization (WHO) on March 11, 2020.