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Columbus sails on 4th and last voyage to present day panama and Honduras
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Beginning of slave trade in the New World
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1,500 Spanish settlers go to Panama
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Overthrow of the king of Spain by Napoleon
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Panama becomes independent from Spain. They then join the confederacy that consists of Columbia, Venezuela, Ecuador, Peru, and Bolivia.
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Panama Becomes part of Columbia when the Gran Columbia Confederacy collapses.
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Te building of the Panama Railway is the first transcontinental railway of the New World.
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France makes a failed attempt to build a canal to Connect the Atlantic and Pacific Ocean.
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Panama splits from Columbia on November 3rd. US buys control of the Panama Canal for nearly a Century.
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Control over the Panama Canal passes from US to Panama control under the Torrijos-Carter Treaty on January 1st.
