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Introduced the concept of individual inherited 'particles' - genes. Chromosomes duplicated and moved during cell division
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The basic structure of DNA was know and that there was only 4 variations of bases. Scientist felt this wasn't enough for the 20 amino acids found in human protein
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Late 40's/early 50's Oswald Avery, Colin Macleod and Maclyn McCarty destroyed different types of molecules to see inherited change in Bacteria
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Erwin Chargaff discovered that in every case the proportions of cytosine and guanine was the same, the same between adenine and thymine
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Linus Pauling, showed that polypeptide chains are held in an alpha-helix shape by hydrogen bonds.
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Rosalind Franklin used X-rays and took a complex picture of a DNA and created a two stranded model- 3D model
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James Watson and Francis Crick created the first accepted 3D model of DNA using others research (Rosalind Franklin). They used the idea of complimentary base pairing etc. They won a Nobel prize for their work