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Was born in Vinci,Italy
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At 15 Leonardo is sent to Florence to work as apprentice to Andrea De Verrocchio.
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20 year-old Leonardo is accepted into the painters' guild of Florence.
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Leonardo is accused of sodomy; he is publicly humiliated although the charges are later dropped.
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The Annunciation is painted. The work, initially credited to Da Vinci, is now believed to have been painted by Lorenzo di Credi.
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Leonardo begins work on The Adoration of the Magi, an altarpiece for the Monastery of San Donato at Scopeto.
He sketches many studies. -
Leonardo moves to Milan to work in the service of the city's duke, Ludovico Sforza. He gains the title of "painter and engineer of the duke.
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Leonardo paints the Virgin of the Rocks.
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Leonardo paints Lady with an Ermine.
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Leonardo begins work on The Last Supper in the refectory of the convent of Santa Maria delle Grazie in Milan.
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The Last Supper is completed.
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With the duke Ludovico Sforza'a fall from power, Da Vinci leaves Milan and spends a short time in Venice.
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Leonardo begins painting the Virgin and Child with Saint Anne, a project that he only finishes after 10 years.
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Leonardo returns to Florence
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Leonardo begins work as senior military architect and general engineer for Cesare Borgia, son of Pope Alexander VI.
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Leonardo is commissioned to paint the Mona Lisa.
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Leonardo is commission to paint a mural for the council hall in Florence's Palazzo Vecchio, which is to be the Battle of Anghiari, a work that would remain unfinished.
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Leonardo paints St. John the Baptist.
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The king of France invites Leonardo to come work for him.
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May 2, Leonardo dies in France.