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Excact date unknown.
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Work on the Gutenberg bible likely began half a decade prior to it's printing in 1454 or 1455.
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Savonarola's Reign began after the Medici family lost power in Florence.
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Although an excact date is unknown, Lorenzo took power of Florence after the death of his father some time in 1469.
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It is believed Leonardo began the painting of The Last Supper atleast three years earlier. He did not work on it continously and it's estimated completetion in 1498 is based upon the last documents reamining un-destroyed over the years referring to The Last Supper's near-completion in 1497.
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Work began on the sculpture around 1501 and is believed to have been completed in 1504.
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Unknown excact date.
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Nooo! Leonardo!
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The Sack of Rome was carried out by the mutinous troops of Charles V. Holy Roman Emperor against the League of Cognac, the alliance of Florence, France, Milan Venice and the Papal States.
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