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1794, Eli Whitney developed a machine that would greatly increase speed of the seed removing process from cotton for fiber, this caused a higher demand of slaves in the south. http://www.history.com/topics/inventions/cotton-gin-and-eli-whitney
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In late 1819, an attempt by congress to stop sectional and political rivalries over the topic of slavery was made. http://www.history.com/topics/missouri-compromise
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William Llyod Garrison published The Liberator in Boston, it's first issue appeared in 1831 on the first of January. https://en.wikipedia.org/wiki/The_Liberator_(newspaper)
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August 1831, a slave rebellion took place in Southampton County, Virginia. The rebellion was also known as the Southampton Insurrection. https://en.wikipedia.org/wiki/Nat_Turner%27s_slave_rebellion
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The Nullification Convention met in 1832. By then, tariffs of 1828 and 1832 were considered unconstitutional, and wouldn't agree within south Carolina after 1833. https://en.wikipedia.org/wiki/Tariff_of_1832
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Created to propose a law to ban slavery in lands gained from Mexico from the Mexican War. Wilmot Proviso was created after a previous treaty attempt had failed. http://www.history.com/topics/wilmot-proviso
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A series of resolutions were introduced in the year 1850 by Senator Henry Clay to avert a crisis going on between the Northern and Southern Colonies. http://www.history.com/topics/compromise-of-1850
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A novel created by Harriet Beecher Stowe about anti-slavery was published in 1852. It laid the groundwork for the Civil War. http://www.history.com/this-day-in-history/uncle-toms-cabin-is-published
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People were allowed into Nebraska and Kansas territories to decide for themselves whether or not to allow slavery in their borders, it's main purpose was to repeal the Missouri Compromise. https://en.wikipedia.org/wiki/Kansas%E2%80%93Nebraska_Act
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The term 'Bleeding Kansas' was used to describe the period of violence during the settlement time in Kansas territory. the Kansas-Nebraska Act soon overturned in 1854, creating a boundary between Slave and Free territory. http://www.history.com/topics/bleeding-kansas
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in 1857, a legal case was brought to the attention of the Surpreme Court dealing with the case of Dred Scott; a slave who resided within a Free State/Territory, but was not granted his freedom. http://www.history.com/this-day-in-history/dred-scott-decision
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A series of several debates were exchanged between Stephen A. Douglas and Abraham Lincoln during the 1858 Illinois State election campaigns. http://www.history.com/topics/lincoln-douglas-debates
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A small riot group led by Abolitionist John Brown goes against a Federal Army in Haper's Ferry, Virginia to attempt to start an armed slave revolt. https://en.wikipedia.org/wiki/John_Brown%27s_raid_on_Harpers_Ferry
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Confederate States consisted of 11 governments of the Southern states that seceded/separated from the Union in 1860-1861, and conducted a major war, only to be defeated in 1865. http://www.history.com/topics/american-civil-war/secession
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Presidential election of November 6th 1860, Abraham Lincoln outvoted John C. Breckinridge, Stephen A. Douglas, and John Bell. https://en.wikipedia.org/wiki/United_States_presidential_election,_1860
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Confederate guns opened fire on Fort Sumter's harbor in the early morning of April 1861. The day after the attack, Major Robert Anderson surrendered, and was evacuated from the fort. http://www.history.com/this-day-in-history/fort-sumter-fired-upon
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In the early to mid 19th century, the U.R was a secret network of routes and safe houses used by African-American slaves to escape to states that disapproved of slavery. https://en.wikipedia.org/wiki/Underground_Railroad