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Gregor Mendel, through his work on pea plants, discovered the fundamental laws of inheritance. He deduced that genes come in pairs and are inherited as distinct units, one from each parent. Gregor Mendel
https://knowgenetics.org/mendelian-genetics/ -
Avery, McLeod, and McCarty showed that DNA is the substance that causes bacterial transformation, in an era when it had been widely believed that it was proteins that served the function of carrying genetic information. Animation of Avery, McLeod, and McCarty experiments
https://cooper7e.sinauer.com/animation0402.html -
When Francis Crick and James Watson modeled the structure of DNA, they used paper cutouts of the bases and metal scraps from a machine shop. Discovery of Structure of DNA
https://www.youtube.com/watch?time_continue=65&v=V6bKn34nSbk&feature=emb_logo -
Marshall Nirenberg won a Nobel Prize in 1968 for his work in deciphering the sequence of DNA bases in a gene. Nobel Prize.org Interview with Dr. Nirenberg
https://www.nobelprize.org/prizes/medicine/1968/nirenberg/interview/ -
In 1977, Frederick Sanger developed the still used “rapid DNA sequencing” technique to determine the order of bases in a strand of DNA. He shared the 1980 Nobel Prize in Chemistry for his contributions to DNA-sequencing methods. Explanation of Sanger Sequencing
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The location of the HD gene, whose mutation causes Huntington’s disease, was mapped to chromosome 4 in 1983, making HD the first disease gene to be mapped using DNA variants in sequence. Solve a puzzle and help genetic disease research at PHYLO
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The Human Genome Project was an international research effort to determine the sequence of the human genome and identify the genes that it contains. The Project was coordinated by the National Institutes of Health and the U.S. Department of Energy. About the Genome Project
https://www.genome.gov/human-genome-project/What -
H. influenzae causes respiratory and other infections and flu. The sequence of its genome revealed the complete instruction book of a free-living organism for the first time. Its sequencing also gave insights on efficient methods for sequencing.
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In 2002, the international Mouse Genome Sequencing Consortium announced their publication of a high-quality draft sequence of the mouse genome. Scientists were able, for the first time, to compare and contrast the human genome sequences with those of another mammal. Mouse Genome completed
https://www.genome.gov/25520486/online-education-kit-2002-mouse-genome-sequenced -
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The project was an international effort to create a detailed catalog of human genetic variation. Scientists sequenced the genomes of a thousand anonymous participants from a number of different ethnic groups. Genomics Fun Facts on Flickr
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The 100,000 Genomes Project is a UK Government project that is sequencing whole genomes from its National Health Service patients. Participants give consent for their genome data to be linked to information about their medical condition and health records. Interview with Genomics England Chief Scientist Mark Caulfield
https://www.youtube.com/watch?v=0c06k9A_29g&feature=emb_logo -
Genomics Crossword Puzzle
https://genomicsintegration.net/data/Texas-Health-Genomics-Crossword-2012.pdf
