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DNA Timeline

  • Friedrich Miescher

    Friedrich Miescher

    • Isolated “nuclein” (DNA with associated proteins) from cell nuclei
    • First to identify DNA as distinct molecule
    • Focusing on tissue chemistry and studying composition of lymphoid cells (white blood cells)
    • Collected bandages covered with pus, then washed in a salt solution = cells lysed and nuclei precipitated out
    • Thought nuclein functioned as cellular storehouse for phosphorus atom
    • Laid ground work for molecular discoveries

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