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Miescher found a way to separate and isolate DNA. In his lifetime there was no use for the nuclei he discovered.
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Muller discovered that X-Rays can disrupt DNA and cause mutations in genes. Sometimes the mutations are even lethal, but he never found out what the mutated gene looked like.
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Avery discovered the Transforming Principle. It stated DNA could change to merge with another type of DNA.
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Discovered that there are DNA ratios in cells are different. It proved Levene’s theory wrong.
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Franklin discovered that you can not crystalize DNA, but you can get different types of DNA fibers. The fibers gave two different distinct diffraction patterns. They showed the basic structure of DNA, and would later be used to make the 3-D model of DNA.
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Alfred Hershey and Martha Chase confirmed that DNA is a genetic material. Prior to that, it was believed DNA carried proteins.
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Watson and Crick discovered the double helix. The first accurate representation of DNA.
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Kornberg isolated an enzyme that synthesized DNA. He made a cell-free system that replicates DNA.
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Frederick found a way to sequence DNA. He found for every sequencing reaction there is 200-500 base pairs of sequence.
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Mario came up with the method that is used to analyze the functions of proteins.