Dna

DNA Historical Timeline- Rezek

  • Friedrich Miescher

    Friedrich Miescher
    Miescher found a way to separate and isolate DNA. In his lifetime there was no use for the nuclei he discovered.
  • Heramn Muller

    Heramn Muller
    Muller discovered that X-Rays can disrupt DNA and cause mutations in genes. Sometimes the mutations are even lethal, but he never found out what the mutated gene looked like.
  • Oswald Avery

    Oswald Avery
    Avery discovered the Transforming Principle. It stated DNA could change to merge with another type of DNA.
  • Erwinn Chargaff

    Erwinn Chargaff
    Discovered that there are DNA ratios in cells are different. It proved Levene’s theory wrong.
  • Rosland Franklin

    Rosland Franklin
    Franklin discovered that you can not crystalize DNA, but you can get different types of DNA fibers. The fibers gave two different distinct diffraction patterns. They showed the basic structure of DNA, and would later be used to make the 3-D model of DNA.
  • Hershey-Chase

    Hershey-Chase
    Alfred Hershey and Martha Chase confirmed that DNA is a genetic material. Prior to that, it was believed DNA carried proteins.
  • Watson and Crick

    Watson and Crick
    Watson and Crick discovered the double helix. The first accurate representation of DNA.
  • Arthur Kornberg

    Kornberg isolated an enzyme that synthesized DNA. He made a cell-free system that replicates DNA.
  • Frederick Sanger

    Frederick Sanger
    Frederick found a way to sequence DNA. He found for every sequencing reaction there is 200-500 base pairs of sequence.
  • Mario Capecchi

    Mario Capecchi
    Mario came up with the method that is used to analyze the functions of proteins.