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Period: to
DNA Exploration
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Linus Pauling
Pauling worked in molecular structure. His contributions to the area of structure built onto the ideas of other biologist, and before long lead to the discovery of DNA structure. He tested the effects of radiactivity on the structure of molecules, most importantly DNA.
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Griffith conducts first major DNA experiment
Fredrick Griffith used pneumonia to research DNA. He found that one strand could be turned into a different strand. But when you mixed the strands the results would result in the death of his test subjects, in this case mice.
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P.A. Levene
Levene studied the structure and functions of nucleotides, and from his studies was able to tell the difference between RNA and DNa aswell as finding that DNA was composed of adenine, guanine, thymine, cytosine, deoxyribose, aswell as a phosphate group.
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Oswald Avery
Avery and collagues discover that the R strain of bacteria can be changed into an S strain. When S strain was exposed to the DNA of an R strain, some of them accepted this DNA, changing them into R strains, other rejected the DNA of the R strain and remained an S strain as they had been before.
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Period: to
Erwin Chargaff
Through conducting many careful experiments, Erwin was able to make up to rules. THe rules he created later lead to the double helix structure found in DNA. His first rule said that in natural DNA the number of guanine units present is equal to the amount of cytosine units and the number or adenine units equals the number of thymine units present.His second rule says that all DNA species are different.
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Rosalind Franklin
Made large contributions to the understanding the structure of DNA, RNA and viruses. She became most famous for her work on DNA because from her findings scientist were able to grasp a much better understanding of how parents pass down traits to there children.
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Hershey and Chase
As results of Hershey and Chases experiment they presented data that showed DNA is infact the genetic material.THey used bacteriophages and a virus, when the bacteriophages, made of mostly DNA and protein, infected virus the DNA entered the virus and the protein did not. After the virus underwent changes they were able to conclude DNA was
infact the genetic material, not the proteins in a cell.
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James Watson
Watson worked in the department of the structure of DNA. Some of his most well known discoveries was testing the effects of mutation on DNA. One of his experiments that lead to some of watson's discoviries used a radioactive phosphate as a tracer to try to determine which molecular components of phage actually infected the target bacteria during infection.
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Francis Crick
Crick is recognized for his part in the work to reveal the genetic code. He took part in the research of watson which included the use of radioactive phosphate as a tracer to determine which molecular components of phage particles actually infect the target bacteria during the infection.
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Maurice Wilkins
Wilkins was another one of the biochemist involved in the studies of Watson and Crick. THere work focused on the molecular structure of DNA. Their experiment included the use of radioactive phosphate as a tracer to determine which molecular components of phage actually infect the target bacteria during the infection.
wikipedia.com
