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Columbus's voyage to the Caribbean in 1492 marked the beginning of contract between Europeans and Native Americans.
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Three small ships sailed from England to establish a colony in Virginia arriving in May 1607. Jamestown became America's first permanent English settlement.
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On December 21, 1620 the Pilgrims began a new Plymouth Colony. The colony was located where the Town of Plymouth, Massachusetts is today.
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New Orleans and everything west of Mississippi belonged to Spain. France gave all her western land to Spain in order to keep from the British.