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The capital city is moved from Philadelphia to Washington, D.C.
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Thomas Jefferson is inaugurated as the third president of the United States.
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The United States nearly doubles in size by paying France $15 million to purchase the Louisiana territory.
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Louis and Clark leave St. Louis, Missouri, on a journey to the West to find a route to the Pacific Ocean.
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James Madison is inaugurated as President of the United States.
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The United States declares war on the British for interference in their expansion to the west.
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James Monroe is inaugurated as the fifth president of the United States.
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Spain agrees to cede the land of Florida to the United States due to issues with resources.
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Maine is admitted as a free state and Missouri is admitted as a slave state. All other lands north of latitude 36º30' are not allowed to be slave states.
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John Quincy Adams is inaugurated as the sixth president of the United States.
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Andrew Jackson is inaugurated as the seventh president of the United States.
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Texas becomes a free nation by declaring independence from Mexico.
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All Texan defenders are killed by the Mexican army laying siege on the Alamo.
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John O'Sullivan uses the term "Manifest Destiny" in an article to represent the idea that the U.S. is entitled to all land stretching to the Pacific Ocean.
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Harriet Tubman escapes slavery and becomes an icon for abolition.
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Abraham Lincoln is elected as the sixteenth president.
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South Carolina secedes from the union due to the federal government's policies and actions regarding state's rights and slavery.
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South Carolina, Mississippi, Florida, Alabama, Georgia, and Louisiana secede from the Union and form the Confederate States of America.
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Confederates attack Fort Sumter in South Carolina and begin the Civil War.
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The Emancipation Proclamation frees all slaves in the Confederate States.
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Confederate general Robert E. Lee surrenders to Ulysses S. Grant.
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Abraham Lincoln is assassinated by John Wilkes Booth at a theater in Washington, D.C.
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A fire broke out in Chicago killing approximately 300 people and destroying thousands of buildings.