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Three ships led by Captain Christopher Newport, the Susan Constant, the Discovery, and the Godspeed. reach Cape Henry on the Virginia Coast.
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The Susan Constant, the Discovery, and the Godspeed, arrive at Jamestown and establish the first English Settlement in the United states.
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Samuel Champlain battles an Iroquois party, discovers Lake Champlain, and claims Vermont for France.
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Henry Hudson sails into New York Harbour.
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Pocahontas marries John Rolfe and this marriage leads to 8 years of peace between colonists and indians.
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Smallpox epidemic begins to wipe out 90% in the Massachusetts Bay Area.
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First African slaves are brought to Jamestown.
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First representative assembly, The House of Burgesses, held in America is elected in Jamestown
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The Plymouth colony in Massachusetts is established.
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The Mayflower Compact is signed.
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The Indian Massacre of 1622 occurs after Chief Opchanacanough and the Powhatan Confederacy attempt to rid the colony of settlers. 300 people were killed.
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The first of eleven vessels leave England for the Puritan colony already established in Salem, and establish the Massachusetts Bay colony.
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Maryland is founded as a Catholic colony.
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Rhode Island is founded as a colony by Roger Williams
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Pequot war begins between Pequot tribe and the Massachusetts, Plymouth, and Saybrook colonies.
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Pequot war ends with the signing of the Treaty of Hartford.
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The English seize New Amsterdam from the Dutch, and rename it New York.