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Leonardo da Vinci creates a design for a two wheeled hoist with a caged gear.
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Galen's works on the human anatomy published in the original Greek.
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Paracelsus pioneers the use of minerals and poisons in medicine.
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Father of Botany, Otto Brunfels publishes the first part of Herbarum Vivae Eicones with realistic illustrations by Hans Weiditz.
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Berengario da Carpi produces Anatomia Carpi, the first anatomical text with illustrations based on dissections of human bodies.
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Ambroise Pare revives the practice of ligature for gunshot wounds.
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Giambattista Canano publishes illustrations of each muscle and its relation with the bones.