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Orcagna creates the " Truimph Of Death "
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Raphael creates the Betrothal of the Virgin at the age of 21.
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In 1450 Georg Purbach begans a series of lectures on astronomy.
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Alchemy is discovered, it was known as the early form of chemistry. It was used to make lead into gold.
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Also, the invention of printing was to have great effect on European society: the facilitated dissemination of the printed word democratized learning and allowed a faster propagation of new ideas.
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The rediscovery of ancient texts was accelerated after the Fall of Constaninople.
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Cosimo de' Medici set a new standard for patronage of the arts, not associated with the church or monarchy
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In 1508 Pope Julius II succeeded in getting the sculptor Michelangelo to agree to continue the decorative scheme of the Sistine Chapel.
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In 1514 Galileo begins to believe that the Earth orbits around the Sun.
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Leonardo Da Vinci creates the Mona Lisa.
