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  5.3 million
- 
  
  Thomas Jefferson became president
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  The US gained the state of Ohio
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  Thomas Jefferson signs "The Act Prohibiting Importation of Slaves of 1807"
- 
  
  James Madison became president
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  7.3 million
- 
  
  the United States gained Louisiana
- 
  
  Second Bank of the United States was the second federally authorized National Bank in the United States
- 
  
  The US gained the state of Indiana
- 
  
  James Monroe became president
- 
  
  Construction begins on the Erie Canal in Rome
- 
  
  The US gained the state of Mississippi
- 
  
  The US gained the state of Illinois
- 
  
  The United States made a treaty with Spain to gain Florida
- 
  
  The US gained the state of Alabama
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  The Missouri Compromise involving primarily the regulation of slavery in the western territories.
- 
  
  The US gained the state of Maine
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  9.6 million
- 
  
  The Santa Fe Trail pioneered in 1821 by William Becknell, it served as a hghway for commercial and military needs
- 
  
  The US gained the state of Missouri
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  President James Monroe introduces the "Monroe Doctrine" stating that if European attempts to recolonize the Americas would be considered a hostile act towards the United States.
- 
  
  John Quincy Adams became president
- 
  
  The Tariff of 1828 was a protective tariff passed by the Congress to protect industry in the northern United States
- 
  
  Andrew Jackson became president
- 
  
  the Indian Removal Act was passed to position on Indian removal, and to gain more land
- 
  
  12.9 million
- 
  
  Nat Turner's Rebellion was a slave rebellion which was the highest number of murders caused by any slave in the South
- 
  
  A bill to renew and modify the charter of the Bank of the United States.
- 
  
  The Texas Revolution was conflict between the government of Mexico and Texas colonists, and throughout that Texas gained the Republic of Texas
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  The Mexican Army battle for the Alamo and the Texans kill approximately 650 Mexican soldiers.
- 
  
  Martin Van Buren became president
- 
  
  The US gained the state of Michigan
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  The US gained the state of Arkansas
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  the forced removal of 15,000-17,000 Cherokee Indians from Georgia on the "Trail of Tears"
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  17 million
- 
  
  William Henry Harrison became president
- 
  
  John Tyler became president
- 
  
  The Oregon Trail was officially started for fur trappers and traders
- 
  
  James K. Polk became president
- 
  
  Ireland's "Potato Famine" results in an influx of Irish immigrants to the United States
- 
  
  The US gained the state of Florida
- 
  
  The US gained the state of Texas
- 
  
  the Mexican War was started because Mexico believed that the land rightfully taken by Texas, was theirs. This then started a war between Mexico and the US
- 
  
  The US gained the state of Iowa
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  After two years of war between Mexico and America, the war was settled and the war was over
- 
  
  The US gained the state of Wisconsin
- 
  
  Zachary Taylor became president
- 
  
  23.2 million
- 
  
  The US gained the state of California