Colorado militia killed 163 Cheyenne and Arapaho Indians causing the natives to create pacts against the US
Red River War
US calvary fought with remaining Comanche wariors for their land throughout the Texas panhandle. All 200 Comanches were killed and the US had minimal Causalities.
Battle of Little Bighorn
Lakota, Northern Cheyenne, and Arapaho tripes where sick of the US taking land and the 7th calvary underestimated their numbers causing them 268 deaths and 55 wounded. This was a huge moral boost for the natives.
Nez Perce War
Americans found gold and good land for cattle in the area of the Nez Perce tribe. A war for land ensued, costing the natives 200 men and forcing the to relocate to a reservation
Battle of Wounded Knee
US army went to disarm the Lakota before they went to a reservation, but shots were fired. US troops were supported by 4 Hotchkiss guns. (first "automatic" firearm) 150 Lakota natives died, and 25 us troops were lost.