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This is the date of Christopher Columbus's birth.
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Nicolas Copernicus (1473-1543) born.
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The Malleus Malificarum (The Hammer of the Witches) is published as an influential guidebook to identifying witches and bringing them to punishment.
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The initial appearance of the heliocentric theory of Nicholas Copernicus (1473-1543) is associated with the private circulation of a manuscript known as the Commentariolus (The Little Commentary) which was published many years later.
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The London College of Physicians is granted a royal charter and functions both as a traditional professional guild as well as a learned society.
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Ferdinand Magellan famously completes the first circumnavigation of the globe.
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March 18 - Newton's health fails, he collapses and borders on death; shortly thereafter, Newton dies at Kensington between 1.00 and 2.00am. On 28 March his body lays in state in Westminster Abbey where he is buried on 4 April.
