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Mendel's paper about genetics is published. He discovered ressecive and dominate traits and how they worked.
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Friedrich Miescher discovered DNA as an acidic substance. He discovered it in the nuclei.
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Walter Flemming describes chromosome behavior during cell division.
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Three men rediscover Mendel's work while doing their own. They had been working on laws of inheritance.
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Walter Sutton observes segragation patterns and sees that they match Mendel's
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Thomas Hunt Morgan and his students studied fruit flies' chromosomes. The dicovered that chromosomes carry genes and determine genetic linkage.
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Some component of heat-killed virulent bacteria can change a non-virulent strain to a virulent strain. This was shown by Fred Griffith.
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Oswald Avery, Colin MacLeod, and Maclyn McCarty all had a part of this. They had showed that DNA can change the properties of cells.It mediates heredity.
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In DNA there are equal amounts of A and T, and C and G. This was discovered by Erwin Chargaff.
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Alfred Hershey & Martha Chase had showed that only the DNA of a virus needs to enter a bacterium to infect it.
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Watson and Crick describe the double helix structure of a DNA molecule.
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Joe Hin Tjio descovers the exact number of chromosomes. There are 46.
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The first restriction enyme becomes purified. This was done by Hamilton Smith.
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A segment of DNA containing a gene from
the African clawed frog Xenopus is fused with DNA from the
bacterium E. coli and placed the resulting DNA back into an
E. coli cell. There, the frog DNA was copied and the gene it
contained directed the production of a specific frog protein. -
Frederick Sanger and colleagues. The Sanger method is most commonly employed in the lab today, with colored dyes used to identify each of the four nucleic acids that make up DNA.
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A genetic marker for Huntington’s disease is found on chromosome 4.
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A method for finding a gene without the knowledge of the
protein it encodes is developed. So called, positional cloning
can help in understanding inherited disease, such as muscular
dystrophy.
