Nanoshell history

History of Pancreatic Cancer Treatments

By Explora
  • First successful removal of a periampullary tumor

    First successful removal of a periampullary tumor

    William Halsted performed this procedure. The tumor is located at the head of the pancreas.
  • First successful pancreaticoduodectomy

    First successful pancreaticoduodectomy

    Walter Kausch performed this procedure. A pancreaticoduodectomy is the removal of all or part of the pancreas along with the duodenum.
  • The Whipple procedure is developed

    The Whipple procedure is developed

    Allen Whipple created this procedure. The Whipple procedure was highly criticized and infrequently performed due to the high mortality rates resulting from its use.
  • Radiation therapy is first used

    Radiation therapy is first used

    Henry Kaplan first treated a cancer patient using this new therapy.
  • Gemcitabine was approved by FDA

    Gemcitabine was approved by FDA

    Gemcitabine is a chemo-drug that can be used in a combination of radiation and chemotherapy for pancreatic cancer.
  • Erlotinib was approved by FDA

    Erlotinib was approved by FDA

    Erlotinib is another drug used in chemotherapy for pancreatic cancer.
  • Clinical trials of combination therapy using gemcitabine and second-generation targeting agents are performed

    Clinical trials of combination therapy using gemcitabine and second-generation targeting agents are performed

    Increased targeting of pancreatic cancer cells became available when Farnesyltransferase inhibitors were discovered. Although these inhibtors have negative side effects on the patient’s immune systems, they have proven to target matrix metalloproteinase and the the K-ras oncogene pathway, which are present in relatively high concentrations in pancreatic tumors.
  • First human trial of LANAPT

    First human trial of LANAPT

  • Development of a method to mass produce gold nanoshells and anti-CA 19-9

    Development of a method to mass produce gold nanoshells and anti-CA 19-9

  • Gold nanoshells and anti CA 19-9 are approved by FDA

    Gold nanoshells and anti CA 19-9 are approved by FDA

  • First successful treatment of pancreatic cancer using LANAPT

    First successful treatment of pancreatic cancer using LANAPT